Artem-Ds Plus Tablets 80/480Mg (1 Box = 1 Strip)(1 Strip = 8 Tablets)
Both components Artemether/ Lumefantrine have their own action site in the malarial parasite
Both components Artemether/ Lumefantrine have their own action site in the malarial parasite. The presence of the endoperoxide bridge in Artemether (generating single oxygen and free radicals, those are very cytotoxic to the plasmodia) appears to be essential for antimalarial activity.
Purpose
Malaria
Ingredients
Artemether , Lumefantrine
Warnings
Caution is advised when administering Artemether + Lumefantrine to patients with severe renal, hepatic or cardiac problems. In such cases, monitoring of the ECG is recommended and steps is advised to be taken to correct any electrolyte disturbances.
Caution is recommended when combining Artemether + Lumefantrine with drugs exhibiting variable patterns of inhibition, induction or competition for CYP3A4 as the therapeutic effects of some drugs could be altered.
Patients who remain averse to food during treatment is advised to be closely monitored as the risk of recrudescence may be greater.
Side Effects
Very Common: Palpitations, headache, dizziness, abdominal pain, anorexia, vomiting, nausea, arthralgia, mylagia, asthenia, fatigue, sleep disorders.Common: Amnesia, paraesthesia, diarrhea, pruritus, rash, cough, electrocardiogram QT prolongation, gait disturbances, insomia.Uncommon: Liver function test increased, clonus, hypoesthesia, ataxia, somnolence.
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Hilton |
| Status | Active |