Atcovate Lotion 0.05% 20Ml
The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear
The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A2Â inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Fluticasone propionate is lipophilic and has a strong affinity for the glucocorticoid receptor. It has weak affinity for the progesterone receptor, and virtually no affinity for the mineralocorticoid, estrogen, or androgen receptors. The therapeutic potency of glucocorticoids is related to the half-life of the glucocorticoid-receptor complex. The half-life of the fluticasone propionate-glucocorticoid receptor complex is approximately 10 hours.
Purpose
Eczema
Ingredients
Fluticasone Propionate
Warnings
It is advised to not be used in the presence of preexisting skin atrophy and is advised to not be used where infection is present at the treatment site. It is advised to not be used in the treatment of rosacea and perioral dermatitis.
This medication is advised to not be used for any disorder other than that for which it was prescribed.
The treated skin area is advised to not be bandaged or otherwise covered or wrapped so as to be occlusive unless directed by the physician.
Side Effects
Common (may affect up to 1 in 10 people) • Irritation or itching. Uncommon (may affect up to 1 in 100 people) • A feeling of burning where the ointment is applied. Very rare (may affect up to 1 in 10,000 people) • If you have psoriasis you may get raised bumps with pus under the skin. This can happen during or after the treatment and is known as pustular psoriasis. • Worsening of condition • Redness • Rash or hives • Stretch marks may develop • Blood vessels under the surface of your skin may become more noticeable • Changes to the colour of your skin • Increased body hair • Skin thinning • Skin wrinkling • Skin dryness • Weight gain and rounding of the face • Obesity
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Atco Pharma |
| Status | Active |
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