Avsar Plus 10/160/12.5Mg Tab

Triple-combination blood pressure tablet with amlodipine, valsartan, and hydrochlorothiazide for resistant hypertension.

PKR 545.00

PKR 517.75

You save: PKR 27.25

Quantity:

SKU: AVSAR_PLUS_10/160/12.5MG_TAB_NV

Category: Medicines

Avsar Plus is a triple-combination antihypertensive containing Amlodipine (calcium channel blocker), Valsartan (angiotensin II receptor blocker), and Hydrochlorothiazide (thiazide diuretic). This fixed-dose combination targets three distinct mechanisms of blood pressure regulation: vasodilation through calcium channel blockade, renin-angiotensin system inhibition, and sodium-water excretion enhancement. The synergistic effect provides superior blood pressure control compared to monotherapy or dual combinations, particularly beneficial for difficult-to-control hypertension.

Purpose

Treatment of essential hypertension not adequately controlled on dual therapy, reduction of cardiovascular event risk (heart attack, stroke, heart failure), prevention of target organ damage from hypertension.

Ingredients

Amlodipine Besylate equivalent to Amlodipine 10mg, Valsartan USP 160mg, Hydrochlorothiazide USP 12.5mg

Warnings

FETAL TOXICITY WARNING - Discontinue immediately if pregnancy detected. Can cause injury and death to developing fetus. Contraindicated in anuria, severe renal/hepatic impairment. Monitor electrolytes (especially potassium), renal function regularly. Risk of hypotension, especially in volume-depleted patients. Avoid with aliskiren in diabetes. May worsen gout. Photosensitivity precautions. Prescription medicine.

Side Effects

Dizziness, peripheral edema (ankle swelling), headache, fatigue, hypokalemia (low potassium), increased urination, dehydration. Less common: hypotension, electrolyte imbalances, hyperuricemia, photosensitivity, muscle cramps.