Baclin Tablets 10Mg (1 Strip = 10 Tablets)
Baclofen is an antispastic agent acting at the spinal level
Baclofen is an antispastic agent acting at the spinal level. A gamma-aminobutyric acid (GABA) derivative, chemically unrelated to other antispastic agents. Baclofen depresses monosynaptic and polysynaptic reflex transmission, probably by stimulating the GABAB-receptors. This stimulation in turn inhibits the release of the excitatory amino acids glutamate and aspartate. Neuromuscular transmission is unaffected by baclofen.The major benefits of baclofen stem from its ability to reduce painful flexor spasms and spontaneous clonus thereby facilitating the mobility of the patient, increasing their independence and helping rehabilitation.Baclofen also exerts an antinociceptive effect. General well being is often improved and sedation is less often a problem than with centrally acting drugs. Baclofen stimulates gastric acid secretion .
Purpose
Muscle Relaxant
Ingredients
Baclofen
Warnings
Baclofen may also exacerbate epileptic manifestations but can be employed provided appropriate supervision and adequate anticonvulsive therapy are maintained.
Baclofen is advised to be used with caution in patients suffering from cerebrovascular accidents or from respiratory or hepatic impairment .
Cases of misuse, abuse and dependence have been reported with baclofen. Caution is advised to be exercised in patients with a history of substance abuse and the patient is advised to be monitored for symptoms of baclofen misuse, abuse or dependence e.g. dose escalation, drug-seeking behaviour, development of tolerance.
Side Effects
• Drowsiness • sleepiness • feeling sick • dry mouth • headache, dizziness or light-headedness • fatigue • excessively weak limbs or feeling tired and exhausted, aching muscles • unsteadiness, trembling or other problems with muscle control • confusion, depression • mood changes with extreme excitement, • hallucinations (seeing or feeling or hearing things that are not really there) or nightmares, • low blood pressure (fainting) • stomach upset including retching, vomiting, diarrhoea or constipation • sleeplessness • skin rash, excessive sweating .
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Genome |
| Status | Active |
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