Cara Tablets 20Mg (1 Strip = 10 Tablets)

Leflunomide is an immunomodulatory drug that may exert its effects by inhibiting the mitochondrial enzyme...

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SKU: CARA_TABLETS_20_MG_30S_NV

Category: Medicines

Leflunomide is an immunomodulatory drug that may exert its effects by inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH), which plays a key role in the de novo synthesis of the pyrimidine ribonucleotide uridine monophosphate (rUMP).

Purpose

Rheumatoid Arthritis

Ingredients

Leflunomide

Warnings

Talk to your doctor, pharmacist or nurse before taking Leflunomide if you have ever suffered from inflammation of the lung (interstitial lung disease).
Advise patient to report signs of infections ; perform washout if infections are severe .
Talk to your doctor, pharmacist or nurse before taking Leflunomide if you have ever had tuberculosis or if you have been in close contact with someone who has or has had tuberculosis. Your doctor may performtests to see if you have tuberculosis.

Side Effects

Common side effects (may affect up to 1 in 10 people) : A slight decrease in the number of white blood cells (leucopenia), - mild allergic reactions, - loss of appetite, weight loss (usually insignificant), - tiredness (asthenia), - headache, dizziness, - abnormal skin sensations like tingling (paraesthesia), - mild increase in blood pressure, - colitis, - diarrhoea, - nausea, vomiting, - inflammation of the mouth or mouth ulcers, - abdominal pain. Uncommon side effects (may affect up to 1 in 100 people) : A decrease in the number of red blood cells (anaemia) and a decrease in the number of blood platelets (thrombocytopenia), - a decrease in the levels of potassium in the blood, - anxiety, - taste disturbances, - urticaria (nettle rash), - tendon rupture, - an increase in the levels of fat in the blood (cholesterol and triglycerides), - a decrease in the levels of phosphate in the blood.Rare side effects (may affect up to 1 in 1,000 people) : An increase in the numbers of blood cells called eosinophiles (eosinophilia); mild decrease in the number of white blood cells (leucopenia); decrease in the number of all blood cells (pancytopenia), - severe increase in blood pressure, - inflammation of the lung (interstitial lung disease), - an increase in some liver results which may develop into serious conditions such as hepatitis and jaundice.