Ceridal 10Mg Tab (100S)

Domperidone peripheral dopamine antagonist for nausea, vomiting, and gastroparesis with prokinetic effects.

PKR 500.00

PKR 475.00

You save: PKR 25.00

Quantity:

SKU: CERIDAL_10MG_TAB_100S_NV

Category: Medicines

Ceridal contains Domperidone, a peripheral dopamine D2 receptor antagonist with prokinetic and antiemetic properties. Unlike centrally-acting antiemetics, domperidone primarily acts in the peripheral chemoreceptor trigger zone and gastrointestinal tract, promoting gastric emptying and enhancing gastrointestinal motility while minimizing central nervous system side effects. The 10mg strength in a 100-tablet package supports both acute and chronic management of nausea, vomiting, and dyspeptic symptoms. Domperidone's peripheral selectivity reduces extrapyramidal side effects common with other dopamine antagonists, though cardiac monitoring considerations exist.

Purpose

Relief of nausea and vomiting symptoms, treatment of dyspeptic symptoms including bloating, epigastric discomfort, reflux, early satiety. Off-label: diabetic gastroparesis, chemotherapy-induced nausea (limited duration).

Ingredients

Domperidone Maleate equivalent to Domperidone 10mg

Warnings

CARDIAC WARNING - May prolong QT interval. Contraindicated in moderate-severe hepatic impairment, conditions where gastric stimulation could be harmful (GI hemorrhage, obstruction, perforation), prolactinoma, concomitant QT-prolonging drugs, significant cardiac conditions. Use lowest dose for shortest duration (max 7 days without medical review). Drug interactions with CYP3A4 inhibitors (azole antifungals, macrolides, protease inhibitors). Monitor for cardiac symptoms. Not for routine prevention. Elderly require careful assessment. Pregnancy/lactation considerations. Prescription medicine.

Side Effects

Dry mouth, headache, diarrhea, abdominal cramps. Serious but rare: QT prolongation, cardiac arrhythmias, extrapyramidal effects (rare), galactorrhea, gynecomastia (with prolonged use).