Cidine Tablets 1Mg (1 Box = 14 Tablets)

Cinitapride is an orthopramide with gastrointestinal prokinetic activity, with considerable muscarinic properties

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SKU: CIDINE_TAB_1MG_14S_NV

Category: Medicines

Cinitapride is an orthopramide with gastrointestinal prokinetic activity, with considerable muscarinic properties. It blocks the presynaptic serotonin receptors and increases its release, resulting in greater serotonergic activity. Though it has discrete antidopaminergic activity, this adds to cinitaprideâ€™s therapeutic effect. Cinitapride efficacy could be due not only to an increase in the pressure of the inferior oesophageal sphincter but also due to its prokinetic effect.

Purpose

Gastroesophageal Reflux Disease

Ingredients

Cinitapride

Warnings

Cinitapride is advised to be used with extreme caution in elderly people due to the increased risk of serious side effects. This medicine may also increase the risk of tardive dyskinesia (a condition characterized by abnormal, involuntary movements of the jaw, lips and tongue) in these people. Appropriate dosage adjustments or replacement with a suitable alternative may be required.
Cinitapride is advised to not be administered in the first three months of pregnancy . Therefore, cinitapride is advised to be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Caution is advised to be exercised in patients with history of gastrointestinal bleeding, mechanical obstruction or perforation, movement disorder, during pregnancy and breastfeeding .

Side Effects

Some patients may notice a slight sedation although cinitapride has not shown sedation while taking the recommended dose. On rare occasion, there may be extrapyramidal effects with spasm in the muscles of the face, neck and tongue which disappear when the treatment is stopped. The following may appear on very rare occasions: - Skin reactions: rash, pruritus. - Gynecomastia. - Very occasionally angioedema.