Clenil For Areosol Ampoule 0.8Mg/2Ml (1 Box = 10 Nebulization Solution)

Beclomethasone dipropionate is a pro-drug with weak glucocorticoid receptor binding affinity

PKR 1113.00

PKR 1057.35

You save: PKR 55.65

Quantity:

SKU: CLENIL_FOR_AREOSOL_08_MG_PER_2_ML_AMPULE_NV

Category: Medicines

Beclomethasone dipropionate is a pro-drug with weak glucocorticoid receptor binding affinity. It is extensively hydrolyzed via esterase enzymes to the active metabolite Beclomethasone-17-monopropionate (B-17-MP), which has high topical anti-inflammatory activity.

Purpose

Asthma

Ingredients

Beclomethasone dipropionate

Warnings

Lack of response or severe exacerbations of asthma is advised to be treated by increasing the dose of inhaled Beclomethasone dipropionate and if necessary, by giving a systemic steroid and/or an antibiotic if there is an infection, together with ÃŸ-agonist therapy .
Special care is necessary for the first months after the transfer until the hypothalamic-pituitary-adrenal (HPA) system has sufficiently recovered to enable the patient to cope with emergencies such as trauma, surgery or infections.
In some patients inhaled Beclomethasone dipropionate may cause hoarseness or throat irritation. It may be helpful to rinse the mouth out with water as soon as possible after inhalation. The use of a spacer device may be considered.

Side Effects

Candidiasis of the throat and mouth may develop in some patients but this can be treated without discontinuation of Beclomethasone therapy. - Hoarseness or throat irritation may also occur. - As with other inhaled therapy, paradoxical bronchospasm with wheezing may occur immediately after dosing. Immediate treatment with an inhaled fast-acting bronchodilator is required. Beclomethasone dipropionate should be discontinued immediately and alternative prophylactic therapy introduced. - Systemic effects of inhaled corticosteroids may occur particularly at high doses prescribed for prolonged periods. These may include adrenal suppression, growth retardation in children and adolescents, decrease in bone mineral density, cataract and glaucoma. - Hypersensitivity reactions including rashes, urticaria, pruritus and erythema and edema of the eye, face, lips and throat (angioedema) have been reported. - Psychiatric disorders including psychomotor hyperactivity, sleep disorders, anxiety, depression, aggression and behavioral changes (predominantly in children).