Daonil Tablets 5Mg (1 Box = 6 Strips) (1 Strip = 10 Tablets)

Both in healthy people and in patients with non-insulin dependent (type 2) diabetes mellitus, glibenclamide lowers...

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SKU: DAONIL_TABLETS_5_MG_6X10S_NV

Category: Medicines

Both in healthy people and in patients with non-insulin dependent (type 2) diabetes mellitus, glibenclamide lowers blood glucose concentration by stimulating insulin release from the betacells of the pancreas. This effect operates in interaction with glucose (improvement in the responsiveness of beta-cells to the physiological glucose stimulus). Glibenclamide is also reported as having extrapancreatic effects: it reduces hepatic glucose production and enhances insulin binding and insulin sensitivity in peripheral tissues.

Purpose

Diabetes

Ingredients

Glibenclamide

Warnings

Epidemiological studies suggest that the administration of glibenclamide is associated with an increased risk of cardiovascular mortality, when compared to treatment with metformin or gliclazide. This risk was especially observed in patients with diagnosed coronary diseases.
Clinical signs of hyperglycaemia are: increased urinary frequency, intense thirst, dryness of the mouth, and dry skin. In exceptional stress situations (e.g. trauma, surgery, febrile infections), blood glucose regulation may deteriorate, and a temporary change to insulin may be necessary to maintain good metabolic control. Persons allergic to other sulfonamide derivatives may develop an allergic reaction to glibenclamide as well.
When starting treatment, the patient must be informed about the effects and risks of Glibenclamide and about its interaction with dietary measures and physical exercise; the importance of adequate cooperation must also be stressed.

Side Effects

Headache, ravenous hunger, nausea, vomiting, lassitude, sleepiness, disordered sleep, restlessness, aggressiveness, impaired concentration, alertness and reactions, depression, confusion, speech disorders, aphasia, visual disorders, tremor, pareses, sensory disturbances, dizziness, helplessness, loss of self-control, delirium, cerebral convulsions, somnolence and loss of consciousness up to and including coma, shallow respiration and bradycardia , sweating, clammy skin, anxiety, tachycardia, hypertension, palpitations, angina pectoris, and cardiac arrhythmias .