Easehale Respules Nebulization Solution 0.025% 2Ml (1 Box = 10 Nebulization Solution)
Ipratropium bromide is an anticholinergic (parasympatholytic) agent it appears to inhibits the vagally mediated...
Ipratropium bromide is an anticholinergic (parasympatholytic) agent it appears to inhibits the vagally mediated reflexes by antagonising the action of acetylcholine, the transmitter agent released from the vagus nerve. Anticholinergics prevent the increase in intracellular concentration of Ca++ which is caused by interaction of acetylcholine with the muscarinic receptor on bronchial smooth muscle. The bronchodilation following inhalation of ipratropium bromide is induced by local drug concentrations sufficient for anticholinergic efficacy at the bronchial smooth muscle and not by systemic concentrations.
Purpose
Chronic Obstructive Pulmonary Disease
Ingredients
Ipratropium Bromide
Warnings
Ipratropium bromide is an anticholinergic and its use may increase intraocular pressure. This may result in precipitation or worsening of narrow-angle glaucoma. Therefore, it is advised to be used with caution in patients with narrow-angle glaucoma. Patients is advised to avoid spraying ipratropium bromide inhaler into the eye.
Ipratropium bromide can produce paradoxical bronchospasm that can be life threatening. If this occurs, treatment with ipratropium bromide is advised to be stopped and other treatments considered.
Hypersensitivity reactions including urticaria, angioedema, rash, bronchospasm, anaphylaxis and oropharyngeal edema, may occur after the a dministration of ipratropium bromide. If such a reaction occurs, therapy with ipratropium bromide is advised to be stopped at once and alternative treatment is advised to be considered.
Side Effects
Common: Headache, dizziness, cough, throat irritation, nausea, dryness of mouth and gastrointestinal motility disorder.Uncommon: Blurred vision, mydriasis, intraocular pressure increased, eye pain, halo vision, conjunctival hyperemia, corneal oedema, glaucoma, anaphylactic reaction, hypersensitivity, angioedema of tongue, lips & face, palpitations, supraventricular tachycardia, bronchospasm, paradoxical bronchospasm, laryngospasm, pharyngeal oedema, dry throat, diarrhea, constipation, vomiting, stomatitis, rash, pruritus and urinary retention.Rare: Accommodation disorder, atrial fibrillation, heart rate increased and urticaria.
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Hudson Pharmaceuticals (PVT.) LTD. |
| Status | Active |