Eglaro Tablets 15Mg (1 Box = 2 Strips) (1 Strip = 7 Tablets)
SGLT2 is the predominant transporter responsible for reabsorption of glucose from the glomerular filtrate back into the...
SGLT2 is the predominant transporter responsible for reabsorption of glucose from the glomerular filtrate back into the circulation. Ertugliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, ertugliflozin reduces renal reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion.
Purpose
Diabetes
Ingredients
Ertugliflozin
Warnings
Consider monitoring for ketoacidosis and temporarily discontinuing ertugliflozin in other clinical situations known to predispose to ketoacidosis (e.g., prolonged fasting due to acute illness or post-surgery). Ensure risk factors for ketoacidosis are resolved prior to restarting ertugliflozin.
Before initiating ertugliflozin, consider factors in the patient history that may predispose them to the need for amputations, such as a history of prior amputation, peripheral vascular disease, neuropathy and diabetic foot ulcers. Counsel patients about the importance of routine preventative foot care. Monitor patients receiving ertugliflozin for signs and symptoms of infection (including osteomyelitis), new pain or tenderness, sores or ulcers involving the lower limbs, and discontinue ertugliflozin if these complications occur .
Insulin and insulin secretagogues (e.g., sulfonylurea) are known to cause hypoglycemia. Ertugliflozin may increase the risk of hypoglycemia when used in combination with insulin and/or an insulin secretagogue. Therefore, a lower dose of insulin or insulin secretagogue may be required to minimize the risk of hypoglycemia when used in combination with ertugliflozin.
Side Effects
Female genital mycotic infections .
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Pharmevo |
| Status | Active |