Flexia Tablets 60Mg (1 Box = 1 Strip)(1 Strip = 10 Tablets)
Etoricoxib is an oral, selective cyclo-oxygenase-2 (COX-2) inhibitor
Etoricoxib is an oral, selective cyclo-oxygenase-2 (COX-2) inhibitor. Etoricoxib produced dose-dependent inhibition of COX-2 without inhibition of COX-1 at doses up to 150mg daily. Etoricoxib does not inhibit gastric prostaglandin synthesis and has no effect on platelet function. Selective inhibition of COX-2 by etoricoxib decreases the synthesis of prostanoid mediators of pain, inflammation and fever with decreased potential for GI toxicity and effects on platelet aggregation.
Purpose
Osteoarthritis
Ingredients
Etoricoxib
Warnings
Patients with significant risk factors for cardiovascular events (e.g., hypertension, hyperlipidemia, diabetes mellitus, smoking) is advised to only be treated with etoricoxib after careful consideration.
COX-2 selective inhibitors are not a substitute for acetylsalicylic acid for prophylaxis of cardiovascular thrombo-embolic diseases because of their lack of antiplatelet effect. Therefore antiplatelet therapies is advised to not be discontinued.
In compromised renal perfusion, administration of etoricoxib may cause a reduction in prostaglandin formation and secondarily, in renal blood flow and thereby impair renal function. Monitoring of renal function in such patients is advised to be considered.
Side Effects
Common : Alveolar osteitis, edema/fluid retention, dizziness, headache, palpitations, arrhythmia, hypertension, bronchospasm, constipation, flatulence, gastritis, acid reflux, diarrhea, dyspepsia, epigastric discomfort, nausea, vomiting, ALT increased, AST increased, ecchymosis, asthenia/fatigue and flu-like disease.Uncommon : Gastroenteritis, upper respiratory infection, urinary tract infection, anemia, leukopenia, thrombocytopenia, hypersensitivity, increase or decrease appetite,weight gain, anxiety, depression, mental acuity decreased, hallucinations, dysgeusia, insomnia, paresthaesia/hypaesthesia, somnolence, blurred vision, conjunctivitis, tinnitus, vertigo, atrial fibrillation, tachycardia, congestive heart failure, non-specific ECG changes, angina pectoris, myocardial infarction, flushing, cerebrovascular accident, transient ischemic attack, hypertensive crisis, vasculitis, cough, dyspnea, epistaxis, abdominal distention, bowel movement pattern change, constipation, dry mouth, gastroduodenal ulcer, peptic ulcer, irritable bowel syndrome, pancreatitis, facial edema, pruritus, rash, erythema, urticaria, muscular cramp/spasm, musculoskeletal pain/stiffness,proteinuria, serum creatinine increased, renal failure/renal insufficiency, chest pain, blood urea nitrogen increased, creatine phosphokinase increased, hyperkalemia and uric acid increased.Rare : Angioedema/anaphylactic/anaphylactoid reactions including shock, confusion, restlessness, hepatitis, hepatic failure, jaundice, Stevens-Johnson syndrome, toxic epidermal necrolysis, fixed drug eruption and blood sodium decreased.
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Ferozsons |
| Status | Active |
Related Products
