Glucovance Tablets 2.5/500Mg (1 Strip = 15 Tablets)
Metformin Hydrochloride and Glibenclamide, two antihyperglycemic agents with complementary mechanisms of action, to...
Metformin Hydrochloride and Glibenclamide, two antihyperglycemic agents with complementary mechanisms of action, to improve glycemic control in patients with type 2 diabetes. Metformin Hydrochloride is an antihyperglycemic agent that improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Glibenclamide appears to lower blood glucose acutely by stimulating the release of insulin from the pancreas, an effect dependent upon functioning beta cells in the pancreatic islets.
Purpose
Diabetes
Ingredients
Glibenclamide , Metformin HCl
Warnings
Renal or hepatic insufficiency may cause elevated drug levels of both Metformin Hydrochloride and Glibenclamide and the hepatic insufficiency may also diminish gluconeogenic capacity, both of which increase the risk of hypoglycemic reactions.
Elderly, debilitated, or malnourished patients and those with adrenal or pituitary insufficiency or alcohol intoxication are particularly susceptible to hypoglycemic effects. Hypoglycemia may be difficult to recognize in the elderly, and in people who are taking betaadrenergic blocking drug.
Safety and effectivenes in pediatric patients have not been established.
Side Effects
Diarrhoea, Headache, Nausea / Vomiting, Abdominal pain and Dizziness.
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Merck |
| Status | Active |
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