Brand: Barrett

Irecon Tablets 75Mg (1 Box = 1 Strip)(1 Strip = 10 Tablets)

Irbesartan : Irbesartan is a potent, orally active, selective angiotensin-II receptor (type AT1) antagonist

PKR 220.00
PKR 209.00
You save: PKR 11.00
SKU: IRECON_TABLETS_75_MG_10S_NV
Category: Medicines

Irbesartan : Irbesartan is a potent, orally active, selective angiotensin-II receptor (type AT1) antagonist. It is expected to block all actions of angiotensin-II mediated by the AT1 receptor, regardless of the source or route of synthesis of angiotensin-II. The selective antagonism of the angiotensin-II (AT1) receptors results in increases in plasma renin levels and angiotensin-II levels, and a decrease in plasma aldosterone concentration. Serum potassium levels are not significantly affected by irbesartan alone at the recommended doses. Irbesartan does not inhibit ACE (kininase-II), an enzyme which generates angiotensin-II and also degrades bradykinin into inactive metabolites. Irbesartan does not require metabolic activation for its activity.

Purpose

Hypertension

Ingredients

Irbesartan

Warnings

There is evidence that the concomitant use of ACE-inhibitors, angiotensin II receptor blockers or aliskiren increases the risk of hypotension, hyperkalaemia and decreased renal function (including acute renal failure). Dual blockade of RAAS through the combined use of ACE-inhibitors, angiotensin II receptor blockers or aliskiren is therefore not recommended.
ACE-inhibitors and angiotensin II receptor blockers is advised to not be used concomitantly in patients with diabetic nephropathy.
As for any patient receiving diuretic therapy, periodic determination of serum electrolytes is advised to be performed at appropriate intervals

Side Effects

Cardiac disorders: Common: increases in blood urea nitrogen (BUN), creatinine and creatine kinase Uncommon: decreases in serum potassium and sodium .Uncommon: syncope, hypotension, tachycardia, oedema.Nervous system disorders: Common: dizziness Uncommon: orthostatic dizziness Not known: headache . Ear and labyrinth disorders: Not known: tinnitus. Respiratory, thoracic and mediastinal disorders: Not known: cough. Gastrointestinal disorders: Common: nausea/vomiting , Uncommon: diarrhoea , Not known: dyspepsia, dysgeusia .

Storage Instructions

Store this medicine at room temperature, away from direct light and heat.

Brand Barrett
Status Active
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