Lamisil Tablets 250Mg (1 Box = 1 Strip)(1 Strip = 10 Tablets)
Terbinafine is an allylamine which has a broad spectrum of antifungal activity
Terbinafine is an allylamine which has a broad spectrum of antifungal activity. At low concentrations Terbinafine tablets is fungicidal against dermatophytes, moulds and certain dimorphic fungi. The activity versus yeasts is fungicidal or fungistatic depending on the species. Terbinafine tablets interfere selectively with fungal sterol biosynthesis at an early stage through inhibition of the enzyme squalene epoxidase. This leads to a deficiency in ergosterol and to an intracellular accumulation of squalene in the fungal cell membrane. Both the deficiency in ergosterol and the accumulation of squalene are responsible for fungal cell death.
Purpose
Fungal Infection
Ingredients
Terbinafine HCl
Warnings
Terbinafine is contraindicated for patients with chronic or active hepatic disease. Before prescribing Terbinafine , a liver function test is advised to be performed and any pre-existing liver disease is advised to be assessed.
Serious skin reactions (e.g. Stevens-Johnson syndrome, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms) have been very rarely reported in patients taking Terbinafine . If progressive skin rash occurs, Terbinafine treatment is advised to be discontinued.
Very rare cases of blood dyscrasias (neutropenia, agranulocytosis, thrombocytopenia, pancytopenia) have been reported in patients treated with Terbinafine tablets. Aetiology of any blood dyscrasias that occur in patients treated with Terbinafine tablets is advised to be evaluated and consideration is advised to be given for a possible change in medication regimen, including discontinuation of treatment with Terbinafine .
Side Effects
Very common (may affect more than 1 in 10 people) • Stomach problems such as loss of appetite, ache, indigestion, feeling bloated or sick • Diarrhoea • Itching, rash or swelling • Pains in the muscles and joints Common (may affect up to 1 in 10 people) • Headache Uncommon (may affect up to 1 in 100 people) • Taste loss and taste disturbance. This usually disappears within several weeks after you stop taking the medicine. However, a very small number of people, (less than 1 in 10,000), have reported that the taste disturbance lasts for some time and, as a result, they go off their food and lose weight.There have also been reports of some people experiencing anxiety or symptoms of depression as a result of these taste disturbances.
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Novartis |
| Status | Active |
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