Mibega Tablets 25Mg (1 Box = 2 Strips) (1 Strip = 10 Tablets)

Mirabegron is an agonist of the human beta-3 adrenergic receptor (AR)

PKR 1512.00

PKR 1436.40

You save: PKR 75.60

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SKU: MIBEGA_TAB_25MG_20S_250_MG_TABLETS_NV

Category: Medicines

Mirabegron is an agonist of the human beta-3 adrenergic receptor (AR). Mirabegron relaxes the detrusor smooth muscle during the storage phase of the urinary bladder fill-void cycle by activation of beta-3 ARwhich increases bladder capacity.

Purpose

Urinary Incontinence

Ingredients

Mirabegron

Warnings

Urinary retention in patients with bladder outlet obstruction (BOO) and in patients taking antimuscarinic medications for the treatment of OAB has been reported in patients taking mirabegron. Mirabegron is advised to be administered with caution to patients with clinically significant BOO. Mirabegron is advised to also be administered with caution to patients taking antimuscarinic medications for the treatment of OAB.
Angioedema of the face, lips, tongue and/or larynx has been reported with mirabegron. In some cases angioedema occurred after the first dose. Cases of angioedema have been reported to occur hours afterthe first dose or after multiple doses. Angioedema associated with upper airway swelling may be life threatening. If involvement of the tongue, hypopharynx or larynx occurs, promptly discontinue mirabegron and initiate appropriate therapy and/or measures necessary to ensure a patent airway .
Caution is advised to be exercised when administering mirabegron in patients with a known history of QT prolongation or patients who are taking medicinal products known to prolong the QT interval.

Side Effects

Common : Urinary tract infection, tachycardia, nausea, constipation, diarrhea, headache and dizziness.Uncommon : Vaginal infection, cystitis, palpitation, atrial fibrillation, dyspepsia, gastritis, urticaria, rash, rash macular, rash popular, pruritis, joint swelling, vulvovaginal pruritus, blood pressure increased, GGTincreased, AST increased and ALT increased.Rare : Eyelid edema, lip edema, leukocytoclastic vasculitis, purpura, angioedema and urinary retention.