Neo-Mercazole Tablets 5Mg (1 Bottle = 100 Tablets)
Carbimazole, a thionamide, is a pro-drug which undergoes rapid and virtually complete metabolism to the active...
Carbimazole, a thionamide, is a pro-drug which undergoes rapid and virtually complete metabolism to the active metabolite, thiamazole, also known as methimazole. The method of action is believed to be inhibition of the organification of iodide and the coupling of iodothyronine residues which in turn suppress the synthesis of thyroid hormones.
Purpose
Hyperthyroidism
Ingredients
Carbimazole
Warnings
Bone marrow depression including neutropenia, eosinophilia, leucopenia and agranulocytosis has been reported. Fatalities with carbimazole-induced agranulocytosis have been reported.
Patients is advised to always be warned about the onset of sore throats, bruising or bleeding, mouth ulcers, fever and malaise and is advised to be instructed to stop the drug and to seek medical advice as soon as possible. In such patients, white blood cell counts is advised to be performed as soon as possible, particularly where there is any clinical evidence of infection.
Carbimazole is advised to be used with caution in patients with mild-moderate hepatic insufficiency. If abnormal liver function is discovered, the treatment is advised to be stopped. The half-life may be prolonged due to the liver disorder.
Side Effects
Sore throat , mouth ulcers , high temperature or fever , itching , increased bruising or bleeding tendency , you are feeling generally unwell or think that you may have an infection , angioedema, a serious allergic reaction with symptoms that may include swollen tongue, lips, face or throat .
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | RAY Pharma (PVT.) LTD. |
| Status | Active |
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