Panadol Cf Day Tablets (1 Strip = 10 Tablets)
Paracetamol works to stop the pain messages from getting through to the brain
Paracetamol works to stop the pain messages from getting through to the brain. It also acts in the brain to reduce fever . Pseudoephedrine is a sympathomimetic with a mixed mechanism of action, direct and indirect. It indirectly stimulates alpha-adrenergic receptors, causing the release of endogenous norepinephrine from the granularity of neurons, while it directly stimulates beta-adrenergic receptors . Codeine binds to mu-opioid receptors, which are involved in the transmission of pain throughout the body and central nervous system . The analgesic properties of codeine are thought to arise from its conversion to Morphine, although the exact mechanism of analgesic action is unknown at this time .
Purpose
Fever & Cough
Ingredients
Paracetamol + Phenylephedrine HCl + Caffeine
Warnings
Caution is advised to be exercised in patients with mild to moderate kidney impairment and in those with hepatic impairment. Underlying liver disease increases the risk of paracetamol-related liver damage.
Cases of hepatic dysfunction/failure have been reported in patients with depleted glutathione levels, such as those who are severely malnourished, anorexic, have a low body mass index or are chronic heavy users of alcohol.
Caution is advised to be exercised in patients with cardiovascular disease, arrhythmias, hypertension, hyperthyroidism, prostatic enlargement, diabetes, glaucoma, phaeochromocytoma, epilepsy, bronchitis, bronchiectasis and bronchial asthma.
Side Effects
Paracetamol : Thrombocytopaenia, Anaphylaxis cutaneous hypersensitivity reactions including amoung others skin rashes, angiodema, stevens johnson syndrome, toxic epidermal necrosis, bronchospasm in patients sensitive to aspirin and other NSAIDs, hepatic dysfuction. Phenylephrine : Nervousness, Headache, Dizziness, Insomnia, Increased blood pressure, Vomiting, nausea, Mydriasis, acute angle closure glaucoma, most likely to occur in those with closed angle glaucoma Tachycardia, Palpitations Allergic reactions (e.g. rash, urticaria, allergic dermatitis) Dysuria, urinary retention. This is most likely to occur in those with bladder outlet obstruction such as prostatic hypertrophy.
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Haleon |
| Status | Active |
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