Penro Iv Injection 500Mg (1 Box = 1 Injection)
Meropenem exerts its bactericidal activity by inhibiting bacterial cell wall synthesis in Gram-positive and...
Meropenem exerts its bactericidal activity by inhibiting bacterial cell wall synthesis in Gram-positive and Gram-negative bacteria through binding to penicillin-binding proteins (PBPs). Meropenem binds to PBPs 2, 3 and 4 of Escherichia coli and Pseudomonas aeruginosa; and PBPs 1, 2 and 4 of Staphylococcus aureus.
Purpose
Bacterial Infection
Ingredients
Meropenem
Warnings
As with all beta-lactam antibiotics, serious and occasionally fatal hypersensitivity reactions have been reported. Before initiating therapy with meropenem, careful inquiry is advised to be made concerning previous hypersensitivity reactions to beta-lactam antibiotics. If a severe allergic reaction occurs, meropenem is advised to be discontinued and appropriate measures is advised to be taken.
Seizures have infrequently been reported during treatment with carbapenems, including meropenem.
Hepatic function is advised to be closely monitored during treatment with meropenem due to the risk of hepatic toxicity (hepatic dysfunction with cholestasis and cytolysis).
Side Effects
Common : Thrombocythemia, headache, diarrhea, vomiting, nausea, abdominal pain, increased transaminases, increased blood alkaline phosphatase, increased blood lactate dehydrogenase, rash, pruritis, inflammation and pain.Uncommon : Oral and vaginal candidiasis, eosinophilia, thrombocytopenia, leucopenia, neutropenia, agranulocytosis, hemolytic anemia, angioedema, anaphylaxis, paraesthesiae, antibiotic-associated colitis, increased blood bilirubin, urticaria, toxic epidermal necrolysis, Stevens Johnson syndrome, erythema multiforme, increased blood creatinine & urea, thrombophlebitis and pain at the injection site.Rare : Convulsions.
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Bosch Pharmaceuticals (PVT.) LTD. |
| Status | Active |
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