Pentasa Tablets 500Mg (1 Strip = 10 Tablets)
Mesalazine has an anti-inflammatory effect through a mechanism that has not yet been fully clarified
Mesalazine has an anti-inflammatory effect through a mechanism that has not yet been fully clarified. Mesalazine inhibits migration of polymorph nuclear leukocytes and lipoxygenase of cells at concentrationsreached in the large intestine during treatment. The production of pro-inflammatory leukotrienes (LTB4 and 5-HETE) in macrophages of the intestinal wall is then inhibited. Mesalazine has been shown to activatePPAR-Y receptors which counteract nuclear activation of intestinal inflammatory responses.
Purpose
Acidity & Ulcers
Ingredients
Mesalazine
Warnings
Following mesalazine treatment, serious blood dyscrasias have been reported rarely. If the patient develops unexplained bleeding, hematoma bruising, purpura, anemia, persistent fever or sore throat, hematological investigations is advised to be performed. If there is suspicion of blood dyscrasia, treatment is advised to be terminated.
In case of existing gastric or duodenal ulcers treatment is advised to begin with caution based on theoretical grounds.
Caution is advised to be used in patients with previous myopericarditis of allergic background regardless of its origin.
Side Effects
Common : Headache, diarrhea, abdominal pain, nausea, vomiting, rash, drug fever, dizziness, arthralgia and dyspepsiaRare : Myocarditis, pericarditis, anemia, tinnitus, paresthesia, flatulence, pruritus, urticaria, myalgia, interstitial nephritis, myocarditis, pancreatitis, abnormal renal , function, leucopenia, thrombocytopenia, agranulocytosis and neutropenia.
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Atco Pharma |
| Status | Active |
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