Pitalo Tablets 2Mg (1 Box = 1 Strip) (1 Strip = 10 Tablets)
Pitavastatin competitively inhibits HMG-CoA reductase, which is a rate-determining enzyme involved with biosynthesis of...
Pitavastatin competitively inhibits HMG-CoA reductase, which is a rate-determining enzyme involved with biosynthesis of cholesterol, in a manner of competition with the substrate so that it inhibits cholesterol synthesis in the liver. As a result, the expression of LDL-receptors followed by the uptake of LDL from blood to liver is accelerated and then the plasma TC decreases. Further, the sustained inhibition of cholesterol synthesis in the liver decreases levels of very low density lipoproteins .
Purpose
Cholesterol Control
Ingredients
Pitavastatin
Warnings
Pitavastatin is advised to be administered with caution in patients with impaired renal function, in elderly patients, or when used concomitantly with fibrates or lipid-modifying doses of niacin.
Pitavastatin therapy is advised to be discontinued if markedly elevated creatine kinase (CK) levels occur or myopathy is diagnosed or suspected.
Pitavastatin therapy is advised to also be temporarily withheld in any patient with an acute, serious condition suggestive of myopathy or predisposing to the development of renal failure secondary to rhabdomyolysis (e.g., sepsis, hypotension, dehydration, major surgery, trauma, severe metabolic, endocrine, and electrolyte disorders, or uncontrolled seizures) .
Side Effects
• Rhabdomyolysis with myoglobinuria and acute renal failure and myopathy (including myositis). • Liver Enzyme Abnormalities •Back Pain • Constipation • Diarrhea • Myalgia • Pain in Extremity
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Genix |
| Status | Active |
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