Renavel Tablets 800Mg (1 Strip = 10 Tablets)

It contains sevelamer, a non-absorbed phosphate binding poly (allylamine hydrochloride) polymer, free of metal and...

PKR 3584.00

PKR 3404.80

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SKU: RENAVEL_800MG_TABLETS_30S_NV

Category: Medicines

It contains sevelamer, a non-absorbed phosphate binding poly (allylamine hydrochloride) polymer, free of metal and calcium. It contains multiple amines separated by one carbon from the polymer backbone. These amines become partially protonated in the intestine and interact with phosphate molecules through ionic and hydrogen bonding. By binding phosphate in the gastrointestinal tract, sevelamer lowers the phosphate concentration in the serum.

Purpose

Dialysis

Ingredients

Sevelamer Hydrochloride

Warnings

Closer monitoring of patients with hypothyroidism co-administered with sevelamer hydrochloride and levothyroxine is recommended .
Patients receiving dialysis are subject to certain risks for infection specific to the dialysis modality. Peritonitis is a known complication in patients receiving peritoneal dialysis (PD) and in a clinical study with sevelamer, a number of peritonitis cases were reported. Therefore, patients on PD is advised to be closely monitored to ensure the reliable use of appropriate aseptic technique with the prompt recognition and management of any signs and symptoms associated with peritonitis.
Cases of serious inflammatory disorders of different parts of the gastrointestinal tract (including serious complications such as haemorrhage, perforation, ulceration, necrosis, colitis and colonic/caecal mass) associated with the presence of sevelamer crystals have been reported . Inflammatory disorders may resolve upon sevelamer discontinuation. Sevelamer hydrochloride treatment is advised to be re-evaluated in patients who develop severe gastrointestinal symptoms .

Side Effects

Very common (may affect more than 1 in 10 people): Nausea, vomiting. Common (may affect up to 1 in 10 people): Diarrhoea, indigestion, abdominal pain, constipation, flatulence. Uncommon (may affect up to 1 in 100 people): Increased acidity of the blood. Very rare (may affect up to 1 in 10000 people): Hypersensitivity.