Rocephin Im Injection 1G (1 Box = 1 Injection)
Ceftriaxone works by inhibiting the mucopeptide synthesis in the bacterial cell wall
Ceftriaxone works by inhibiting the mucopeptide synthesis in the bacterial cell wall. The beta-lactam moiety of Ceftriaxone binds to carboxypeptidases, endopeptidases, and transpeptidases in the bacterial cytoplasmic membrane. These enzymes are involved in cell-wall synthesis and cell division. By binding to these enzymes, Ceftriaxone results in the formation of defective cell walls and cell death.
Purpose
Bacterial Infection
Ingredients
Ceftriaxone Sodium
Warnings
An immune mediated hemolytic anemia has been observed in patients receiving cephalosporin class antibacterials including Ceftriaxone.
Patients with impaired vitamin K synthesis or low vitamin K stores (e.g, chronic hepatic disease and malnutrition) may require monitoring of prothrombin time during Ceftriaxone treatment. Vitamin K administration (10 mg weekly) may be necessary if the prothrombin time is prolonged before or during therapy.
Prolonged use of Ceftriaxone may result in overgrowth of nonsusceptible organisms. Careful observation of the patient is essential. If superinfection occurs during therapy, appropriate measures is advised to be taken.
Side Effects
Hypersensitivity reactions such as allergic skin reactions and anaphy lactic reactions, secondary infections with yeast, fungi or resistant organisms as well as changes in blood cell counts.Mycosis of the genital tract, neutropenia, leucopenia, eosinophilia, thrombocytopenia, anaemia (including haemolytic anaemia), slight prolongation of prothrombin time, anaphy lactic (e.g. bronchospasm) and anaphy lactoid reactions, headache, dizziness, Increase in serum liver enzymes (AST, ALT, alkaline phosphatase), rigors and pyrexia.
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Roche Pakistsn LTD |
| Status | Active |
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