Ruling+ Sachets 40Mg (1 Box = 10 Sachets)
Omeprazole reduces gastric acid secretion through a unique mechanism of action
Omeprazole reduces gastric acid secretion through a unique mechanism of action. Omeprazole belongs to a class of anti-secretory compounds - the substituted benzimidazoles that do not exhibit anti-cholinergic or H2 histamine antagonistic properties. It inhibits secretion of gastric acid by irreversibly blocking the enzyme system of hydrogen/potassium adenosine triphosphatase (H+/K+ATPase), the proton pump of the gastric parietal cell. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.
Purpose
Gastroesophageal Reflux Disease
Ingredients
Omeprazole + Sodium Bicarbonte
Warnings
Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-term with omeprazole .
Sodium bicarbonate is advised to be used with caution in patients with Bartter''''s syndrome, hypokalemia, respiratory alkalosis, and problems with acid-base balance. Long- term administration of bicarbonate with calcium or milk can cause milk-alkali syndrome .
Omeprazole powder for oral suspension contains sodium in the form of sodium bicarbonate. This is advised to be taken into consideration for patients on a sodium restricted diet .
Side Effects
Common : Central and peripheral nervous system: Headache. Gastrointestinal: Diarrhea, constipation, abdominal pain, nausea/vomiting and flatulence.Uncommon : Central and peripheral nervous system: Dizziness, paraesthesia, somnolence, insomnia and vertigo.Hepatic: Increased liver enzymesSkin: Rash and/or pruritis, urticariaOther: MalaiseRare : Central and peripheral nervous system: Reversible mental confusion, agitation,aggression, depression and hallucinations, predominantly in severely ill patients.Endocrine: Gynecomastia
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | High Q |
| Status | Active |
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