Spiromide Tablets 20Mg (1 Strip = 10 Tablets)
Furosemide: Furosemide is a short-acting diuretic; diuresis usually commences within one hour and lasts for four to six...
Furosemide: Furosemide is a short-acting diuretic; diuresis usually commences within one hour and lasts for four to six hours. Spironolactone: Spironolactone, a competitive inhibitor of aldosterone, increases sodium excretion whilst reducing potassium loss at the distal renal tubule. It has a slow and prolonged action; maximum response being usually attained after 2 – 3 days treatment.
Purpose
Heart Failure
Ingredients
Furosemide , Spironolactone
Warnings
Treatment with Lasilactone necessitates regular medical supervision. Particularly careful monitoring is necessary in patients with hypotension or patients liable to electrolyte deficiency. Where indicated, steps is advised to be taken to correct hypotension or hypovolaemia before commencing therapy.
Regular monitoring of serum sodium, potassium, creatinine and glucose is generally recommended during therapy; particularly close monitoring is required in patients at high risk of developing electrolyte imbalances or in case of significant additional fluid loss (e.g. due to vomiting, diarrhoea or intense sweating). Hypovolaemia or dehydration as well as any significant electrolyte and acid-base disturbances must be corrected. This may require temporary discontinuation of Lasilactone.
dministration of Lasilactone is advised to be avoided in the presence of a raised serum potassium. Frequent checks of the serum potassium level are necessary in patients with impaired renal function and a creatinine clearance below 60 ml/min per 1.73 m2Â body surface area as well as in cases where Lasilactone is taken in combination with certain other drugs (e.g. triamterene, amiloride, potassium supplements or non-steroidal anti-inflammatory drugs) which may lead to an increase in potassium levels.
Side Effects
Blood and lymphatic system disorders : Not known: Bone marrow depression has been reported as a rare complication and necessitates withdrawal of treatment ; Nervous system disorders : Not known: Paraesthesia may occur , Dizziness, fainting and loss of consciousness (caused by symptomatic hypotension), headache. Renal and urinary disorders : Not known: Serum calcium levels may be reduced; in very rare cases tetany has been observed. Nephrocalcinosis / Nephrolithiasis has been reported in premature infants ; Increased production of urine may provoke or aggravate complaints in patients with an obstruction of urinary outflow.
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
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