Sumatec Tablets 50Mg (1 Box = 1 Strip)(1 Strip = 2 Tablets)
Sumatriptan has been demonstrated to be a selective vascular 5-hydroxytryptamine-1-(5-HT 1D) receptor agonist with no...
Sumatriptan has been demonstrated to be a selective vascular 5-hydroxytryptamine-1-(5-HT 1D) receptor agonist with no effect at other 5-HT receptor (5-HT2–7) subtypes. The vascular 5-HT 1D receptor is found predominantly in cranial blood vessels and mediates vasoconstriction. In animals, sumatriptan selectively constricts the carotid arterial circulation, but does not alter cerebral blood flow. The carotid arterial circulation supplies blood to the extracranial and intracranial tissues such as the meninges and dilatation and/or oedema formation in these vessels is thought to be the underlying mechanism of migraine in man. In addition, experimental evidence suggests that sumatriptan inhibits trigeminal nerve activity. Both these actions may contribute to the anti-migraine action of sumatriptan in humans.
Purpose
Migraine
Ingredients
Sumatriptan
Warnings
It is advised to only be used where there is a clear diagnosis of migraine. It is not indicated for use in the management of hemiplegic, basilar or ophthalmoplegic migraine.
Following administration, it can be associated with transient symptoms including chest pain and tightness which may be intense and involve the throat (see Adverse Reactions). Where such symptoms are thought to indicate IHD appropriate evaluation is advised to be carried out .
It is advised to be used with caution in patients with a history of seizures or other risk factors which lower the seizure threshold.
Side Effects
Nervous System Disorders Common: Dizziness, drowsiness,sensory disturbance including paraesthesia and hypoaesthesia. Vascular disorders Common: Transient increases in blood pressure arising soon after treatment. Flushing. Respiratory, Thoracic and Mediastinal Disorders Common: Dyspnoea. Gastrointestinal Disorders Common: Nausea and vomiting occurred in some patients but the relationship to sumatriptan is not clear. Musculoskeletal and Connective Tissue Disorders : The following symptom is usually transient and may be intense and can affect any part of the body including the chest and throat: Common: Sensations of heaviness. General Disorders and Administration Site Conditions The following symptoms are usually transient and may be intense and can affect any part of the body including the chest and throat: Common: Pain, sensations of heat or cold, pressure or tightness. The following symptoms are mostly mild to moderate in intensity and transient: Common: Feelings of weakness, fatigue
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Platinum |
| Status | Active |
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