Tamsolin-S Tablets 0.4Mg+6 Mg (1 Strip = 10 Tablets)

Tamsulosin HCl: Tamsulosin HCl is an a1-adrenoceptor (AR) antagonist

PKR 2875.00

PKR 2731.25

You save: PKR 143.75

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SKU: TAMSOLIN_S_TABLETS_04_6MG_20S_NV

Category: Medicines

Tamsulosin HCl: Tamsulosin HCl is an a1-adrenoceptor (AR) antagonist. It binds selectively and competitively to postsynaptic a1-ARs, in particular to subtypes a1a and a1d and is a potent antagonist in lower urinary tract tissues. Solifenacin succinate: Solifenacin succinate is a competitive and selective antagonist of muscarinic receptors and has no relevant affinity for various other receptors, enzymes and ion channels tested. Solifenacin succinate has the highest affinity for muscarinic M3-receptors, followed by muscarinic M1- and M2- receptors.

Purpose

Benign Prostatic Hyperplasia

Ingredients

Tamsulosin HCl + Solifenacin succinate

Warnings

Other causes of frequent urination (heart failure or renal disease) is advised to be assessed before treatment is initiated. If a urinary tract infection is present, appropriate antibacterial therapy is advised to be started.
QT prolongation and Torsade de Pointes have been observed in patients with risk factors, such as pre-existing long QT syndrome and hypokalemia, who are treated with solifenacin succinate.
Angioedema with airway obstruction has been reported in some patients on tamsulosin HCl + solifenacin succinate. If angioedema occurs, treatment is advised to be discontinued and not restarted. Appropriate therapy and/or measures is advised to be taken .

Side Effects

Tamsulosin HCl : Common: Dizziness, ejaculation disorder including retrograde ejaculation and ejaculation failure. Uncommon: Headache, orthostatic hypotension, rhinitis, constipation, nausea, diarrhea, vomiting, pruritus, rash, urticaria and asthenia. Rare: Syncope and angioedema. Solifenacin succinate : Very common: Dry mouth. Common: Constipation, nausea, dyspepsia, abdominal pain and blurred vision. Uncommon: Gastro esophageal reflux diseases, dry throat, urinary tract infection, cystitis, somnolence, dysgeusia, dry eyes, fatigue, peripheral edema, nasal dryness, dry skin and difficulty in micturation. Rare: Colonic obstruction, fecal impaction and urinary retention, dizziness, headache, vomiting, pruritus and rash.