Telox Tablets 300Mg (1 Strip = 10 Tablets)
The pharmacological activity of oxcarbazepine is primarily exerted through the metabolite (MHD)
The pharmacological activity of oxcarbazepine is primarily exerted through the metabolite (MHD) . The mechanism of action of oxcarbazepine and MHD is thought to be mainly based on the blockade of voltage-sensitive sodium channels, thus resulting in stabilisation of hyperexcited neural membranes, inhibition of repetitive neuronal firing, and diminishment of propagation of synaptic impulses. In addition, increased potassium conductance and modulation of high-voltage activated calcium channels may also contribute to the anticonvulsant effects. No significant interactions with brain neurotransmitter or modulator receptor sites were found.
Purpose
Seizures
Ingredients
Oxcarbazepine
Warnings
Class I (immediate) hypersensitivity reactions including rash, pruritus, urticaria, angioedema and reports of anaphylaxis have been received in the post-marketing period. Cases of anaphylaxis and angioedema involving the larynx, glottis, lips and eyelids have been reported in patients after taking the first or subsequent doses of Oxcarbazepine. If a patient develops these reactions after treatment , the drug is advised to be discontinued and an alternative treatment started.
Very rare cases of hepatitis have been reported, which in most cases resolved favourably. When a hepatic event is suspected, liver function is advised to be evaluated and discontinuation of oxcarbazepine is advised to be considered. Caution is advised to be exercised when treating patients with severe hepatic impairment.
Discontinuation of the medicinal product is advised to be considered if any evidence of significant bone marrow depression develops.
Side Effects
Very common (may affect more than 1 in 10 people): • tiredness; headache; dizziness; drowsiness; feeling sick (nausea); being sick (vomiting); double vision. Common (may affect up to 1 in 10 people): • weakness; memory disturbances; impaired concentration; apathy; agitation; confusion; blurred vision; visual disturbance; constipation; diarrhoea; stomach (abdominal) pain; acne; hair loss, balance disturbances; weight increased; speech disorder. Uncommon (may affect up to 1 in 100 people): • High blood pressure; hives. • You may also have raised levels of liver enzymes while taking oxcarbazepine.
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Platinum |
| Status | Active |
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