Ultivair-M Rotacaps 50+150+160Mcg (1 Box = 3 Strips) (1 Strip = 10 Tablets)

Indacaterol is a selective beta2-adrenergic agonist. Its pharmacological effects are at least in part attributable to stimulation of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3�, 5�-adenosine monophosphate (cAMP). In the lung, increased cAMP levels cause relaxation of bronchial smooth muscle, resulting in bronchodilation. Although beta2-receptors are the predominant adrenergic receptors in bronchial smooth muscle and beta1-receptors are the predominant receptors in the human heart, there are also beta2- adrenergic receptors in the human heart comprising 10% to 50% of the total adrenergic receptors. The precise function of beta2-adrenergic receptors in the heart is unclear, but their presence raises the possibility that even highly selective beta2-adrenergic agonists may have cardiac effects. Glycopyrronium is an inhaled long-acting muscarinic receptor antagonist (anticholinergic) for once-daily maintenance bronchodilator treatment of COPD. Parasympathetic nerves are the major bronchoconstrictive neural pathway in airways, and cholinergic tone is the key reversible component of airflow obstruction in COPD. Glycopyrronium works by blocking the bronchoconstrictor action of acetylcholine on airway smooth muscle cells, thereby dilating the airways.Mometasone is one of a group of medicines called topical corticosteroids. Mometasone topical is classified as a �potent corticosteroid�. These medicines are put on the surface of the skin to reduce the redness and itchiness caused by certain skin problems.