Vonnp Tablets 10Mg (1 Strip = 10 Tablets)
Vonoprazan is a potassium competitive acid blocker (P-CAB) and does not require activation by acid
Vonoprazan is a potassium competitive acid blocker (P-CAB) and does not require activation by acid. It inhibits H+, K+-ATPase in a reversible and potassium-competitive manner. Vonoprazan has a strong basicity and resides on the acid production site of gastric parietal cells for a long time, thereby inhibiting gastric acid production. Vonoprazan exerts a strong inhibitory effect on formation of mucosal damage in upper part of the gastrointestinal tract.
Purpose
Acidity & Ulcers
Ingredients
Vonoprazan
Warnings
In the maintenance of healing of reflux esophagitis, Vonoprazan is advised to be administered only to the patients who repeat recurrence and recrudescence of the condition. Administration to the patients who do not necessitate maintenance of healing is advised to be avoided.
When the healing is maintained over a long period and when there is no risk of recurrence, the dose reduction to a dose of 10mg from a dose 20mg, or suspension of administration is advised to be considered.
Vonoprazan is advised to be administered with care in patients with renal disorders as a delay in the excretion of Vonoprazan may occur, which may result in an increase in the concentration of Vonoprazan in the blood.
Side Effects
Diarrhea, constipation, drug hypersensitivity (including anaphylactic shock), drug eruption, urticaria, hepatotoxicity, jaundice, rash, nausea, abdominal distension, gamma-glutamyl transferase increased, AST increased, Liver function test abnormal, ALT increased, ALP increased, LDH increased, ? - GPT increased, edema and eosinophilia.
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | Horizon |
| Status | Active |
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