Xiga Tablets 5Mg (1 Strip = 7 Tablets)
Sodium-glucose cotransporter 2 (SGLT2), expressed in the proximal renal tubules, is responsible for the majority of the...
Sodium-glucose cotransporter 2 (SGLT2), expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Dapagliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, dapagliflozin reduces reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion.
Purpose
Diabetes
Ingredients
Dapagliflozin
Warnings
Insulin and insulin secretagogues are known to cause hypoglycemia. It can increase the risk of hypoglycemia when combined with insulin or an insulin secretagogue. Therefore, a lower dose of insulin or insulin secretagogue may be required to minimize the risk of hypoglycemia when these agents are used in combination with Dapagliflozin.
It is advised to not be used in patients with active bladder cancer. In patients with prior history of bladder cancer, the benefits of glycemic control versus unknown risks for cancer recurrence with dapagliflozin is advised to be considered.
It increases the risk of genital mycotic infections. Patients with a history of genital mycotic infections were more likely to develop genital mycotic infections.
Side Effects
Infections and infestations : Common: Vulvovaginitis, balanitis and related genital infections, Urinary tract infection (including pyelonephritis and urosepsis) Uncommon: Fungal infection Metabolism and nutrition disorders . Very common: Hypoglycaemia (when used with sulphonylurea or insulin) Uncommon: Volume depletion, Thirst Rare: Diabetic ketoacidosisNervous system disorders : Common: DizzinessGastrointestinal disorders : Uncommon: Constipation, Dry mouth Skin and subcutaneous tissue disorders Common: Rash Musculoskeletal and connective tissue disorders : Common: Back pain Not Known: Fracture of BoneRenal and urinary disorders Common: Dysuria, Polyuria Uncommon: Nocturia, Renal impairmentReproductive system and breast disorders Uncommon: Vulvovaginal pruritus, Pruritus genital
Storage Instructions
Store this medicine at room temperature, away from direct light and heat.
| Brand | CCL |
| Status | Active |